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. 2022 Jul 22;13:942785. doi: 10.3389/fgene.2022.942785

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Copyright © 2022 Li, Li, Zhang and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of Cupr-RLs prognostic signature in HNSC. (A) The least absolute shrinkage and selection operator (LASSO) Cox regression analysis. (B) Lasso coefficient values and vertical dashed lines were calculated at the best log (lambda) value. (C) Univariate Cox regression analysis supported the remarkable prognostic significance of the Cupr-RLs. (D–M) K–M curves showed different OS with different expression levels of the 10 Cupr-RLs. (N) Corrplot displayed the relationship between the 10 Cupr-RLs with 19 cuproptosis-related genes. *p < 0.05, **p < 0.01, ***p < 0.001.