TABLE 2.

Summary data of 13 fetal pigs successfully cannulated and maintained using a pumped AP circuit. Data are presented by increasing GA and are expressed as mean ± SD. Δ Weight for fetal pigs was only calculated for animals that survived ≥24 h on the pumped AP circuit.

GA before (days)	GA after (days)	Duration on AP (hours)	Weight before (g)	Weight after (g)	Δ Weight (g)	Sex (M, F)	Reason for termination	Oxygenator
93	95	36.7	390	450	60	F	Fetal movement occluded UV flow	P
98	98	3.4	450	450	E	M	Heart failure	P
100	101	14.1	505	NA	NA	M	Mechanical failure (pump)	P
100	101	15.1	520	620	E	M	Heart failure	Q
100	102	49.4	590	750	160	F	Heart failure	P
101	104	70.0	762	1190	428	M	Mechanical failure (oxygenator)	Q
102	109	177.8	480	1176	696	M	Hydrops, cardiac dysfunction	P
105	108	68.5	610	NA	NA	NA	Mechanical failure (oxygenator)	P
105	105	17.1	676	NA	E	M	Fetal movement occluded UV flow	P
105	108	53.5	690	NA	NA	M	Fetal movement occluded UV flow	P
105	105	4.2	730	730	E	M	Thrombosis development in circuit	P
105	106	21.1	780	879	E	M	Equipment failure (sweep-gas supply)	P
107	110	72.5	820	876	56	F	Fetal movement occluded UV flow	P
102 ± 4	104 ± 4	46.4 ± 46.8	616 ± 139	792 ± 272 (n = 9)	280 ± 277 (n = 5)

The bold letters represent MEAN ± SD.

NA, not available; M, male; F, female; GA, gestational age; E, excluded from Δ weight analysis; P, Paragon neonatal commercially available ECMO oxygenator; Q, Quadrox-I commercially available bypass oxygenator.