. 2022 Jul 22;13:915316. doi: 10.3389/fpsyt.2022.915316

Table 2.

Regression models: relationship between repetitive negative thinking (RNT) and baseline network connectivity strength.

	Salience network				Default mode network				Left frontoparietal network				Right frontoparietal network
Model summary
Model 1	R² = 0.588, F change = 29.925, Sig. F change (p = ..) <0.001**				R² = 0.588, F change = 29.925, Sig. F change (p = ..) <0.001**				R² = 0.588, F change = 29.925, Sig. F change (p = ..) <0.001**				R² = 0.588, F change = 29.925, Sig. F change (p = ..) <0.001**
Model 2	R² =0.588, F change = 0.001, Sig. F change (p = ..) = 0.974				R² = 0.588, F change = 0.012, Sig. F change (p = ..) = 0.913				R² = 0.597, F change = 4.195, Sig. F change (p = ..) = 0.042*				R² = 0.592, F change = 1.941, Sig. F change (p = ..) = 0.165
Model 3	R² = 0.590, F change = 0.408, Sig. F change (p = ..) = 0.747				R² = 0.596, F change = 1.204, Sig. F change (p = ..) = 0.310				R² = 0.597, F change = 0.108, Sig. F change (p = ..) = 0.955				R² = 0.609, F change = 2.761, Sig. F change (p = ..) = 0.043*
Full model results	Model 2				Model 2				Model 2				Model 3
	B	SE B	β	p-value	B	SE B	β	p-value	B	SE B	β	p-value	B	SE B	β	p-value
Constant	15.115	3.037		<0.001**	15.402	3.885		<0.001**	9.521	3.39		0.006**	12.533	3.949		0.002**
Age (years)	−0.015	0.048	−0.018	0.75	−0.017	0.049	−0.02	0.726	0.036	0.05	0.041	0.469	0.02	0.047	0.023	0.668
Sex (male/female)	−0.289	1.203	−0.012	0.81	−0.315	1.213	−0.013	0.795	−0.166	1.185	−0.007	0.889	−0.364	1.184	−0.015	0.759
Level of education
No vs. middle	1.402	3.482	0.019	0.688	1.463	3.53	0.02	0.679	0.837	3.452	0.012	0.809	0.35	3.448	0.005	0.919
Low vs. middle	−0.715	2.047	−0.017	0.727	−0.701	2.049	−0.017	0.732	−0.78	2.024	−0.019	0.7	−0.713	2.048	−0.017	0.728
High vs. middle	0.413	1.328	0.016	0.756	0.421	1.327	0.017	0.752	0.385	1.308	0.015	0.769	0.246	1.316	0.01	0.852
Subject group (dummy var)
SR	6.693	2.258	0.245	0.003**	6.663	2.27	0.244	0.004**	7.271	2.236	0.266	0.001**	1.444	4.127	0.053	0.727
ND	10.666	1.842	0.364	<0.001**	10.638	1.859	0.363	<0.001**	11.101	1.834	0.379	<0.001**	15.455	4.204	0.528	<0.001**
CM	11.337	2.153	0.398	<0.001**	11.314	2.156	0.397	<0.001**	11.871	2.13	0.417	<0.001**	9.715	4.164	0.341	0.021*
IDS-SR	0.417	0.053	0.546	<0.001**	0.417	0.053	0.546	<0.001**	0.409	0.052	0.536	<0.001**	0.43	0.052	0.563	<0.001**
Within network connectivity	−0.004	0.121	−0.002	0.974	−0.014	0.129	−0.006	0.913	0.39	0.191	0.112	0.042*	0.241	0.173	0.073	0.165
Subject group x connectivity strength
SR vs. HC	N.S.				N.S.				N.S.				0.763	0.486	0.245	p = 0.120
ND vs. HC													−0.695	0.422	−0.278	p = 0.103
CM vs. HC													0.214	0.407	0.074	p = 0.601
SR vs. ND													1.429	0.503	0.594	p = 0.006**
CM vs. ND													0.831	0.418	0.423	p = 0.050
CM vs. SR													−0.477	0.463	−0.22	p = 0.305

Dependent variable: PTQ sum score.

Model 1: predictors: constant, age, sex, level of education, subject group, IDS-SR.

Model 2: predictors from step 1 + baseline network connectivity strength.

Model 3: predictors from step 2 + interaction between subject group and baseline network connectivity strength.

CM: comorbidity group; HC: healthy controls; IDS-SR: Inventory of Depressive Symptomatology Self Report; ND: neurodevelopmental group; N.S.: no significant interaction; PTQ: Perseverative Thinking Questionnaire; Sig.: significant; SR: stress-related group; var: variables.

*p < 0.05.

**p < 0.01.