Skip to main content
. 2022 Aug 5;21:145. doi: 10.1186/s12933-022-01582-w

Table 3.

Univariate and multivariate Cox regression analysis for predicting the primary endpoint

Variables Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
GRACE score 1.0253 1.0182 to 1.0325 < 0.0001 1.0202 1.0117 to 1.0288 < 0.0001
Female 1.5832 1.0334 to 2.4255 0.0348 1.3103 0.8403 to 2.0431 0.2332
BMI 0.9528 0.8841 to 1.0268 0.2050
Smoking 0.7895 0.5222 to 1.1936 0.2623
Previous PCI 1.3968 0.7428 to 2.6268 0.2997
Hypertension 1.3202 0.8409 to 2.0728 0.2274
Diabetes mellitus 1.2838 0.8433 to 1.9544 0.2440
TyG index 1.4961 1.1437 to 1.9571 0.0033 1.6028 1.1900 to 2.1588 0.0019
HDL-C 0.9716 0.4767 to 1.9805 0.9368
LDL-C 0.9249 0.7572 to 1.1297 0.4441
bSS 1.0537 1.0324 to 1.0755 < 0.0001 1.0244 0.9992 to 1.0502 0.0574
ICR 1.9863 1.2077 to 3.2669 0.0069 1.2399 0.7231 to 2.1259 0.4345
LVEF 0.9448 0.9269 to 0.9629 < 0.0001 0.9773 0.9548 to 1.0003 0.0530
AMI 1.9438 1.2533 to 3.0148 0.0030 0.8695 0.5326 to 1.4196 0.5761
β-blockers 0.9299 0.5975 to 1.4473 0.7475
Diuretics 3.2982 2.1419 to 5.0787 < 0.0001 1.5413 0.9234 to 2.5727 0.0979
ACEI/ARB 1.2600 0.8330 to 1.9057 0.2737
Insulin 1.4863 0.7696 to 2.8704 0.2380

The primary endpoint was defined as a composite of all-cause death and nonfatal myocardial infarction. HR, hazard ratio; CI, confidence interval; GRACE score, Global Registry of Acute Coronary Events score; the TyG index, the triglyceride-glucose index; BMI, body mass index; FBG, fasting blood glucose; HDL-C, high density lipoprotein; LDL-C, low density lipoprotein; CTO, chronic total occlusion; ICR, incomplete revascularization; LVEF, left ventricular ejection fraction; AMI, acute myocardial infarction; bSS, baseline SYNTAX score; rSS, residual SYNTAX score; ACEI/ARB, angiotensin converting enzyme inhibitor/angiotensin receptor blocker