Fig. 5.

Muscle regeneration capacity of PDGFRβ lineage cells decrease during aging. A, B Images representing GFP + cells centrally nucleated muscle fibers in young and old muscles 5 days after CTX injury. The images in (B) are higher magnification of the images in (A). C Quantification of regenerated GFP + muscle fibers in skeletal muscle of young and old mice after injury. D Images representing GFP and eMyHC staining. E Quantification of eMyHC + muscle fibers. F Quantification of both GFP + and eMyHC + muscle fibers. N = 6, error bars indicate ‘mean + SD’, *p < 0.05. In panel (A), all scale bars = 200 µm; in panel (B) and (D), all scale bars = 50 µm