Table 4.
Independent clinical agreement validation study using rN-ELISA IgG.
| Positivesamples | Negativesamples | Sensitivity %(CI 95%) | Specificity %(CI 95%) | Accuracy %(CI 95%) | |
|---|---|---|---|---|---|
| Studya | qPCR + (n = 52) | Before pandemic (n = 36) | 84.6 (72.5-92.0) % | 100(90.4-100.0)% | 93.2(85.8-97.5)% |
| Studyb | qPCR + (n = 68) | PCR- (n = 30) | 88.2 (78.5-93.9) % | 100(88.7-100.0)% | 91.3(82.8-96.4)% |
| Studyc | qPCR+/DPP+ (n = 48) | Before pandemic (n = 128) | 95.7 (85.7-99.5) % | 97.7(93.3-99.5)% | 96.0(92.0-98.4)% |
a
Laboratory of Virology (USP).
b
Laboratory of Respiratory Viruses and Measles (Fiocruz-RJ).
c
Laboratory of Diagnostic Technology (Fiocruz-RJ).