Table 3.

Effect of aqueous root extract of Euclea divinorum on body weight, temperature and packed cell volume of P. berghei infected mice in the 4-day suppressive test.

Groups	Body weight			Rectal temperature			Packed cell volume
	D0	D4	(%) change	D0	D4	(%) change	D0	D4	(%) change
CON	28.54 ± 0.97	26.44 ± 1.15	−7.34	36.67 ± 0.18	35.55 ± 0.21	−3.05	53.29 ± 1.34	50.07 ± 1.37	−6.04
CQ25 mg/kg	29.86 ± 1.04	31.06 ± 0.85	4.02a3	36.68 ± 0.27	37.12 ± 0.19	1.20a3	50.83 ± 1.65	50.72 ± 1.59	−0.22a3
100 mg/kg	28.86 ± 1.76	28.12 ± 1.85	−2.56a1b1e1	36.60 ± 0.18	35.97 ± 0.51	−1.72b2	56.02 ± 3.18	53.86 ± 3.41	−3.86b2e1
200 mg/kg	29.24 ± 2.62	29.58 ± 2.70	1.16a3	37.03 ± 0.26	37.10 ± 0.25	0.19a2	58.02 ± 1.63	56.83 ± 1.66	−2.05a3
400 mg/kg	29.43 ± 1.67	30.65 ± 1.65	4.15a3	37.08 ± 0.13	37.28 ± 0.87	0.54a2	53.73 ± 1.07	53.03 ± 1.34	−1.3a3

Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 100 mg/kg; d, to 200 mg/kg; e, to 400 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; CON, control; CQ, chloroquine; D0, pretreatment value on day 0; D4, post- treatment value on day 4.