Table 5.

Effect of aqueous root extract of Euclea divinorum on body weight, temperature and packed cell volume of P. berghei infected mice in the curative test.

Groups	Body weight			Rectal temperature			Packed cell volume
	D3	D7	(%) change	D3	D7	(%) change	D3	D7	(%) change
CON	29.59 ± 1.46	26.50 ± 1.65	−10.44	36.00 ± 0.36	34.92 ± 0.31	−3.00	53.04 ± 1.69	47.99 ± .1.89	−9.52
CQ25 mg/kg	30.18 ± 1.41	29.67 ± 1.55	−1.69a3	35.43 ± 0.54	35.78 ± 0.25	0.99a2	51.14 ± 1.62	51.23 ± 1.52	0.18a3
100 mg/kg	28.17 ± 1.63	26.33 ± 1.66	−6.53	36.67 ± 0.23	36.53 ± 0.19	−0.38a1	52.71 ± 2.66	50.00 ± 842.5	−3.55a3b2e1
200 mg/kg	27.66 ± 0.45	26.58 ± 0.44	−3.90a2	36.33 ± 0.38	36.53 ± 0.38	0.55a2	53.99 ± 2.95	53.01 ± 2.94	−1.82a3
400 mg/kg	30.02 ± 1.40	29.12 ± 1.20	−2.99a2	36.62 ± 0.28	36.88 ± 0.23	0.71a2	53.08 ± 3.26	52.67 ± 3.27	−0.77a3

Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 100 mg/kg; d, to 200 mg/kg; e, to 400 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; CON, control; CQ, chloroquine; D3, pretreatment value on day 0; D7, post- treatment value on day 4.