Table 5.
Comparison of anchors selected using expert rationale compared to selection according to highest area under the receiver operator characteristic (ROC) curve
| EORTC QLQ-C30 scale | Method | SCNS-LF59 anchor | Cut-Off Score | AUC (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|---|---|
| Global quality of life | Expert | Feeling unwell a lot of the time + Not being able to do the things you used to do | 71 | 0.78 (0.71–0.85) | 0.78 (0.68–0.86) | 0.69 (0.64–0.75) |
| AUC | Changes to usual routine and lifestyle | 71 | 0.76 (0.70–0.82) | 0.74 (0.66–0.83) | 0.72 (0.72–0.78) | |
| Physical functioning | Expert | Physical and daily living needs | 97 | 0.79 (0.73–0.85) | 0.80 (0.71–0.89) | 0.61 (0.54–0.67) |
| AUC | Work around the home | 90 | 0.82 (0.74–0.89) | 0.79 (0.79–0.98) | 0.75 (0.49–0.55) | |
| Emotional functioning | Expert | Psychological needs | 71 | 0.79 (0.74–0.84) | 0.71 (0.64–0.79) | 0.70 (0.64–0.77) |
| AUC | Feelings of sadness | 79 | 0.85 (0.81–0.90) | 0.88 (0.82–0.93) | 0.63 (0.55–0.70) | |
| Social functioning | Expert | Changes to usual routine and lifestyle + Changes in other peoples attitudes towards you | 92 | 0.81 (0.75–0.86) | 0.82 (0.75–0.90) | 0.70 (0.64–0.77) |
| AUC | Changes to usual routine and lifestyle | 92 | 0.84 (0.79–0.88) | 0.86 (0.79–0.93) | 0.71 (0.65–0.77) |
EORTC QLQ-C30 European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, SCNS-LF59 supportive care needs survey long form 59, AUC area under the ROC curve, CI confidence interval