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CDxs targeting PD-L1 protein expression for NSCLC
| FDA-approved companion diagnostic | FDA-approved therapeutic products | |||
|---|---|---|---|---|
| Keytruda® (pembrolizumab) | Libtayo® (cemiplimab-rwlc) | Tecentriq® (atezolizumab) | Opdivo® (Nivolumab) + Yervoy® (ipilimumab) |
|
| PD-L1 IHC 22C3 pharmDx | x | x | – | – |
| Ventana PD-L1 (SP142) assay | – | – | x | – |
| PD-L1 IHC 28–8 pharmDX | – | – | – | x |
| VENTANA PD-L1 (SP263) assay | – | – | x | – |
