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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Allergy. 2022 Mar 14;77(8):2534–2548. doi: 10.1111/all.15276

Figure 3. Dichotomous pattern of CRTH2+ and CCR6+ pTeff cells in PA individuals.

Figure 3.

A. Scatterplot of the average signal of CRTH2+ pTeff cell versus CCR6+ pTeff cell gene expression. Shown are genes whose transcription has been up-regulated (red) or down-regulated (blue) by a factor of 2. B. Heatmap of the top differentially expressed genes between the sorted pTeff cell subset. Data are shown in z score–scaled values. C. Expression levels of transcripts associated with TH2A and TH1/TH17 signaling in CRTH2+ (red) and CCR6+ (blue) pTeff cells. Each dot represents distinct individuals. Differences between groups were analyzed by using the two-sided Mann-Whitney test. * p < 0.05, ** p < 0.01, *** p <0.001