Figure 6.

Compute times for the different combinations of methods and nuclear family designs from the multiethnic GENEVA study on CL/P. Results are based on a subset of the genetic data: 8,015 genotyped/imputed SNPs in the region chr8:128344410‐132105518 that includes the known cleft locus 8q24. GDT, generalized disequilibrium test; gTDT, genotypic TDT; SNP, single nucleotide polymorphism; TDT, transmission disequilibrium test