TABLE 2.
Clinical outcomes, outcomes from the EEG evaluation, and correlations between clinical outcomes and EEG analysis at baseline among patients with neuropsychiatric symptoms and probable dementiaa
| EEG at baseline |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| α |
β |
δ |
θ |
|||||||
| Variable | N | Mean | r | p | r | p | r | p | r | p |
| Mini-Mental State Examination | 65 | 21.0 | −0.12 | 0.35 | −0.21 | 0.09 | 0.08 | 0.52 | 0.01 | 0.95 |
| Clinical Dementia Rating Scale | 65 | 7.9 | 0.06 | 0.64 | 0.04 | 0.76 | 0.03 | 0.84 | −0.05 | 0.68 |
| Neuropsychiatric Inventory | ||||||||||
| Total | 65 | 52.6 | −0.09 | 0.48 | −0.09 | 0.48 | 0.25 | 0.04 | −0.02 | 0.88 |
| Delusions | 65 | 4.7 | −0.16 | 0.20 | 0.22 | 0.07 | 0.21 | 0.10 | −0.06 | 0.62 |
| Hallucinations | 65 | 3.2 | −0.18 | 0.15 | −0.05 | 0.71 | 0.18 | 0.15 | 0.14 | 0.28 |
| Agitation | 65 | 4.2 | −0.10 | 0.42 | −0.14 | 0.27 | 0.26 | 0.04 | −0.11 | 0.39 |
| Depression | 65 | 5.5 | −0.06 | 0.66 | 0.01 | 0.94 | 0.16 | 0.19 | 0.00 | 0.99 |
| Anxiety | 65 | 5.9 | 0.08 | 0.55 | 0.00 | 1.00 | 0.07 | 0.58 | −0.08 | 0.51 |
| Euphoria | 65 | 0.6 | 0.03 | 0.80 | −0.19 | 0.14 | 0.02 | 0.89 | 0.09 | 0.46 |
| Apathy | 65 | 8.1 | −0.08 | 0.55 | −0.12 | 0.32 | 0.21 | 0.09 | −0.02 | 0.87 |
| Disinhibition | 65 | 3.1 | −0.14 | 0.28 | −0.13 | 0.30 | 0.19 | 0.14 | 0.03 | 0.84 |
| Irritability | 65 | 4.4 | −0.15 | 0.22 | −0.16 | 0.22 | 0.27 | 0.03 | −0.02 | 0.86 |
| Aberrant motor behavior | 65 | 4.2 | 0.05 | 0.67 | −0.05 | 0.67 | 0.03 | 0.78 | −0.10 | 0.45 |
| Nighttime behavior | 65 | 4.6 | 0.02 | 0.90 | −0.08 | 0.52 | 0.01 | 0.93 | 0.07 | 0.56 |
| Appetite | 65 | 4.0 | 0.09 | 0.49 | 0.01 | 0.94 | −0.12 | 0.34 | 0.03 | 0.82 |
| Cohen-Mansfield Agitation Inventory | ||||||||||
| Total | 65 | 46.5 | 0.01 | 0.91 | −0.06 | 0.65 | 0.18 | 0.15 | −0.19 | 0.13 |
| Physical aggressive behavior | 65 | 11.8 | −0.22 | 0.08 | −0.19 | 0.13 | 0.27 | 0.03 | 0.05 | 0.70 |
| Physical nonaggressive behavior | 65 | 16.8 | 0.06 | 0.65 | 0.08 | 0.54 | 0.11 | 0.38 | −0.31 | 0.01 |
| Verbal aggressive behavior | 65 | 5.0 | −0.20 | 0.11 | −0.25 | 0.04 | 0.33 | 0.01 | 0.07 | 0.56 |
| Verbal nonaggressive behavior | 65 | 12.9 | −0.02 | 0.89 | −0.06 | 0.62 | 0.17 | 0.17 | −0.12 | 0.35 |
| EEG at baseline | ||||||||||
| Alpha | 65 | 0.32 | – | – | – | – | – | – | – | – |
| Beta | 65 | 0.14 | – | – | – | – | – | – | – | – |
| Delta | 65 | 0.24 | – | – | – | – | – | – | – | – |
| Theta | 65 | 0.30 | – | – | – | – | – | – | – | – |
Spearman’s correlation coefficients between clinical outcomes and EEG outcomes are presented. Bold denotes statistically significant correlation.