Table 3.
Baseline characteristics of participants in JUPITER-CVD case-control substudy.
| JUPITER-CVD | Controls | Cases | P-value† |
|---|---|---|---|
| N | 415 | 415 | |
| Age (years) * | 70.0 (64.0, 75.0) | 70.0 (64.0, 76.0) | 7.2e-1 |
| Women (%) | 28.4 | 28.4 | 1.0 |
| White (%) | 91.3 | 83.9* | 1.0e-3 |
| Current smokers (%) | 11.1 | 23.4* | 4.0e-6 |
| BMI (kg/m2) * | 28.4 (25.6, 31.3) | 27.2 (24.0, 30.9) † | 2.0e-3 |
| BMI categories | 1.0e-3 | ||
| < 25 kg/m2 (%) | 20.8 | 32.0 | |
| 25 to 29.9 kg/m2 (%) | 44.9 | 38.6 | |
| ≥ 30 kg/m2 (%) | 34.3 | 29.4 | |
| HDL-C (mg/dL) * | 49.0 (40.0, 61.0) | 47.0 (40.0, 59.0)† | 3.4e-2 |
| LDL-C (mg/dL) * | 109.0 (94.0, 120.0) | 107.0 (93.0, 119.0) | 4.0e-1 |
| Total-C (mg/dL) * | 187.0 (167.5, 201.0) | 184.0 (166.0, 198.0) | 1.5e-1 |
| Triglycerides (mg/dL) * | 116.0 (82.0, 162.5) | 118.0 (86.0, 166.5) | 4.0e-1 |
| hs-CRP (mg/L) * | 4.3 (2.9, 6.9) | 4.7 (3.0, 8.2) | 8.3e-2 |
| Main study intervention assignment (%) | 46.7 | 39.8† | 4.2e-2 |
| Physical activity | 1.5e-1 | ||
| Rarely/Never (%) | 47.0 | 56.9 | |
| Less than once a week (%) | 4.8 | 3.9 | |
| Once a week (%) | 7.0 | 5.5 | |
| 2-3 times a week (%) | 18.8 | 14.9 | |
| 4-6 times a week (%) | 10.4 | 8.9 | |
| Daily (%) | 12.0 | 9.9 |
*
Median (IQR).
†
P-value for statistical test comparing controls vs. cases.
‡
Data available only for 97 cases and 89 controls.
Abbreviations: BMI – body mass index; LDL-C – low density lipoprotein cholesterol; HDL-C – high density lipoprotein cholesterol; Total-C – total cholesterol; hs-CRP – high-sensitivity C-reactive protein.