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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Nature. 2022 Jul 27;608(7921):217–225. doi: 10.1038/s41586-022-04994-6

Extended Data Figure 1. Accompaniment to Figure 1.

Extended Data Figure 1.

a. Hypothetical Eco1 wild-type ncRNA-linked RT-DNA structure. b. Hypothetical Eco1 v32 ncRNA-linked RT-DNA structure and hypothetical duplexed RT-DNA prespacer structure. Nucleotides that are altered from wild-type Eco1 are shown in orange. c. Hypothetical Eco1 v35 ncRNA-linked RT-DNA structure and hypothetical duplexed RT-DNA prespacer structure. Nucleotides that are altered from wild-type Eco1 are shown in green.