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. 2022 Aug 7;37(5):704–715. doi: 10.1016/j.virs.2022.07.014

Table 6.

Comparison between the omicron group and the Delta and Beta groups.

Omicron (n ​= ​310) Delta (n ​= ​96) Beta (n ​= ​326) F/H/χ2 P value
Age(y) 35 (11–53)a,b,c 42.5 (28–56.5) 52.5 (42–64) 104.1613 <0.0001
Gender
 Female 174 (56.13) 53 (55.21) 158 (48.47)
 Male 136 (43.87) 43 (44.79) 168 (51.53)
Vaccination, dose 2 (2–3) 2 (2–2) 0 (0–0) 556.4369 <0.0001
Clinical classifications <0.0001
 Asymptomatic 10 (3.23)b,c 4 (4.17) 102 (31.29)
 Mild 179 (57.74) 48 (50.00) 53 (16.26)
 Moderate 118 (38.06) 43 (44.79) 171 (52.45)
 Severe 3 (0.97) 1 (1.04) 0 (0.00)
WBC, ​× ​109/L 5.405 (4.36–7.01)a,b,c 6.18 (5–7.35) 5.04 (4.05–6.25) 24.6653 <0.0001
LYMPH, ​× ​109/L 1.48 (1–2.01) 1.2 (0.5–2.5) 1.555 (1.19–1.95) 4.8005 0.0907
N%, % 55.35 (45.7–64.65) 59.7 (50.8–67.2) 56.95 (50.8–64.3) 6.2088 0.0449
CRP mg/L 2.86 (0.91–7.37)b,c 2.44 (0.50–7.68) 0.5 (0.499–5.67) 23.2142 <0.0001
IL–6, pg/mL 6.5 (4.7–10.1) 2.84 (1–5.62) 5.22 (2.43–16.87) 47.6800 <0.0001
PCT, ng/mL 0.05 (0.04–0.08)a,b 0.03 (0.02–0.04) 0.03 (0.02–0.05) 86.2541 <0.0001
CD4, cell/μL 548.42 (366.23–788.86) 618.5 (425–776) 581.5 (462.5–841.5) 1.5923 0.4511
CD8, cell/μL 334.28 (186.65–519.16) 372 (286–526) 347 (241–490) 2.5548 0.2788
IgG 0.87 (0.24–20.99)a,b 0.49 (0.43–0.58) 0.39 (0.06–6.25) 20.6799 <0.0001
IgM 2.0625 (0.195–29.94)b,c 3.15 (0.47–17.11) 1.1 (0.08–7.41) 22.0542 <0.0001
Symptoms
Fever 75.2992 <0.0001
 Yes 122 (39.35) a,b,c 59 (61.46) 58 (17.79)
 No 188 (60.65) 37 (38.54) 268 (82.21)
Cough 73.0771 <0.0001
 Yes 151 (48.71) a,b,c 82 (85.42) 117 (35.89)
 No 159 (51.29) 14 (14.58) 209 (64.11)
Sore throat 87.0197 <0.0001
 Yes 118 (38.06) b,c 30 (31.25) 24 (7.36)
 No 192 (61.94) 66 (68.75) 302 (92.64)
Feeble 1.0775 0.5835
 Yes 29 (9.35) 7 (7.29) 35 (10.74)
 No 281 (90.65) 89 (92.71) 291 (89.26)
Headache 7.8568 0.0197
 Yes 21 (6.77)a 15 (15.63) 25 (7.67)
 No 289 (93.23) 81 (84.38) 301 (92.33)
Muscular soreness 0.4752
 Yes 16 (5.16) 7 (7.29) 14 (4.29)
 No 294 (94.84) 89 (92.71) 312 (95.71)
Stuffy nose 36.9124 <0.0001
 Yes 28 (9.03) a,b,c 20 (20.83) 8 (2.45)
 No 282 (90.97) 76 (79.17) 318 (97.55)
Running nose 18.8361 <0.0001
 Yes 31 (10.00) b,c 17 (17.71) 14 (4.29)
 No 279 (90.00) 79 (82.29) 312 (95.71)
Taste loss 82.6751 <0.0001
 Yes 2 (0.65) a,c 21 (21.88) 9 (2.76)
 No 308 (99.35) 75 (78.13) 317 (97.24)
Anosmia 93.0728 <0.0001
 Yes 5 (1.61) a,c 23 (23.96) 6 (1.84)
 No 305 (98.39) 73 (76.04) 320 (98.16)
Diarrhea 22.1437 <0.0001
 Yes 10 (3.23) a,c 14 (14.58) 12 (3.68)
 No 300 (96.77) 82 (85.42) 314 (96.32)
Others 254.8405 <0.0001
 Yes 21 (6.77) a,b,c 81 (84.38) 64 (19.63)
 No 289 (93.23) 15 (15.63) 262 (80.37)

Note: "a" indicates that the difference between omicron group and delta group are statistically significant; "b" indicates that the difference between omicron group and beta group are statistically significant; "c" indicates that the difference between delta group and beta group are statistically significant.

WBC: white blood cell; LYMPH: lymphocyte count; N%: neutrophil percentage; CRP: C-reactive protein; IL-6: interleukin-6.

Data are shown as number (%), mean ± ​standard deviation, or mean (range). P ​< ​0.05 considered the difference to be statistically significant in the three groups.