Table 5.
Treatment response and outcomes
| Demographics | n = 37a | % | pEFS | P = |
|---|---|---|---|---|
| Dexamethasone response | ||||
| Negative | 17 | 65.00 ± 12.68% | 0.0442 | |
| Positive | 20 | 23.44 ± 10.61% | ||
| DGR | 23 | 60.71 ± 10.87% | 0.0269 | |
| DPR | 14 | 15.71 ± 10.18% | ||
| BM status at TP1 | ||||
| M1 | 34 | 43.09 ± 9.52% | - | |
| M2 or M3 | 3 | - | ||
| FCM-MRD level at TP1 | ||||
| < 0.01% | 22 | % | 55.55 ± 11.24% | 0.0221 |
| ≥ 0.01% | 15 | % | 22.86 ± 12.90% | |
| < 1% | 24 | % | 52.38 ± 10.70% | 0.0175 |
| ≥ 1% | 13 | % | 15.39 ± 13.01% | |
| PCR-MRD level at TP1 | ||||
| Negative | 13 | % | 76.92 ± 11.69% | 0.0031 |
| Positive | 24 | % | 19.13 ± 9.43% | |
| FCM-MRD level at TP2 | ||||
| < 0.01% | 25 | % | 57.69 ± 12.01% | < 0.0001 |
| ≥ 0.01% | 12 | % | 8.33 ± 7.98% | |
| PCR-MRD level at TP2 | ||||
| Negative | 23 | % | 64.17 ± 10.93% | < 0.0001 |
| Positive | 14 | % | 8.33 ± 7.93% | |
a patients without TRM