Table 2.

PANS symptom profiles at Baseline

PANS symptoms	Presence of symptoms at baseline in percent (n = 10)	Mean value PANS score
Major PANS criteria
Obsessive- compulsive symptoms	10 (100%)	3.8
Eating restriction	8 (80%)	2.4
Minor PANS criteria
1. Anxiety symptoms
Separation anxiety	9 (90%)	2.9
General anxiety	10 (100%)	3.6
Irrational fears/phobias	8 (80%)	3.0
Panic episodes	9 (90%)	2.5
2. Emotional lability, depression
Emotional lability, mood swings	10 (100%)	3.8
Depression with/without suicidal/self-injurious thoughts	8 (80%)	2.2
3. Increased irritability or aggressive behavior	10 (100%)	3.9
4. Behavioral regression
Behavioral regression (behavior atypical for actual age)	8 (80%)	2.4
Change in personality	10 (100%)	3.3
5. School performance, concentration/learning
Difficulties in attention, concentration or learning	9 (90%)	3.0
Loss of academic skills (math, reading, writing)	8 (80%)	3.1
Confusion	0%	0
6A. Sensory symptoms	10 (100%)	3.6
6B. Hallucinations	2 (20%)	0.7
6C. Motor symptoms
Dysgraphia	6 (60%)	1.9
Motoric hyperactivity	9 (90%)	3.0
Piano playing movements	2 (20%)	0.2
Simple motor/vocal tics	7 (70%)	2.0
Complex motor/vocal tics	4 (40%)	0.9
7A. Urinary symptoms	4 (40%)	1.0
7B. Sleep disturbance, fatigue
Sleep problems	7 (70%)	1.8
Extreme tiredness or fatigue	8 (80%)	2.7
7C. Dilated pupils	7 (70%)	1.7
Body pain	7 (70%)

The PANS symptom severity scores are rated between 0 (no symptoms) and 5 (extreme symptoms)