Table 6.
According to the Results of GWAS SNVs with p-value < 5E-07 Were Selected for Replication Testing in Another Population
| Indicator | Indicator | Gene | SNP ID | Alleles | MA | MAF | Func | β | SE | p value of GWAS | p |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hemocyte | WBC | LINC02101, PLK2 | rs2964173 | T /C | T | 0.045 | Intergenic | −0.005 | 0.072 | 1.33E-07 | 0.941 |
| NEUT | UNC5C | rs78843681 | A /G | A | 0.021 | Intronic | −0.171 | 0.106 | 6.42E-08 | 0.105 | |
| XYLT1/NPIPA7 | rs7195345 | G /C | G | 0.085 | Intergenic | 0.014 | 0.056 | 3.58E-07 | 0.801 | ||
| BASO | EMSY/LRRC32 | rs144735144 | A /G | A | 0.041 | Intergenic | 0.0001 | 0.077 | 1.12E-07 | 0.997 | |
| Red blood cells | RBC | STAP1 | rs191799779 | T /A | T | 0.013 | Downstream | −0.041 | 0.113 | 2.19E-07 | 0.715 |
| C15orf53/C15orf54 | rs2912390 | T /C | T | 0.321 | Intergenic | 0.006 | 0.037 | 2.75E-07 | 0.871 | ||
| RDW% | LOC100506474, LINC00276 | rs118103202 | A /T | A | 0.208 | Intergenic | −0.018 | 0.040 | 3.49E-07 | 0.656 | |
| RDW | LINC00578 | rs1875098 | A /G | A | 0.023 | ncRNA_intronic | 0.005 | 0.105 | 2.36E-07 | 0.963 | |
| CCDC157 | rs35289401 | T /C | T | 0.126 | Intronic | 0.007 | 0.047 | 4.21E-08 | 0.878 | ||
| Hemoglobin | MCH | ARHGAP25 | rs10208669 | A /G | A | 0.362 | Intronic | −0.008 | 0.046 | 3.13E-07 | 0.860 |
| NRIP1/USP25 | rs12482879 | C /G | C | 0.376 | Intergenic | 0.024 | 0.045 | 1.18E-07 | 0.598 | ||
| HBS1L/MYB | rs1331309 | G /T | G | 0.328 | Intergenic | 0.231 | 0.046 | 1.10E-07 | 6.42E-07* | ||
| MCHC | CBLN1/C16orf78 | rs148933121 | C /G | C | 0.045 | Intergenic | 0.016 | 0.057 | 4.55E-07 | 0.785 |
Notes: p value < 0.05 indicates statistical significance; “*” and bolding indicates statistical significance.
Abbreviations: WBC, white blood cell count; NEUT%, neutrophil percentage; EO%, eosinophil percentage; BASO%, basophils percentage; BASO, absolute value of basophils; RBC, red blood cell count; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW%, red cell distribution width CV; RDW, red blood cell distribution width SD; N, number.