Table 1 |.
Case ID | Age (years) | Sex | Diagnosis | PFC neurons (MDA-amplified) | Hippocampus (HC) CA1 neurons (MDA-amplified) | PFC neurons (PTA-amplified) |
---|---|---|---|---|---|---|
Younger neurotypical controls | ||||||
1278 | 0.4 | M | Neurotypical | 9 | − | 3 |
5817 | 0.6 | M | Neurotypical | 4 | − | 3 |
4638 | 15.1 | F | Neurotypical | 10 | − | − |
1465 | 17.5 | M | Neurotypical | 24 | − | 4 |
5532 | 18.4 | M | Neurotypical | 4 | − | − |
5559 | 19.8 | F | Neurotypical | 5 | − | 3 |
4643 | 42.2 | F | Neurotypical | 10 | − | − |
5087 | 44 | M | Neurotypical | 4 | 5 | 3 |
936 | 49.2 | F | Neurotypical | 3 | − | 3 |
73 | 5 | 19 | ||||
Aged neurotypical controls | ||||||
5451 | 57 | F | Neurotypical | 5 | 5 | 3 |
5666 | 65 | M | Neurotypical | − | − | 3 |
5943 | 69 | M | Neurotypical | 5 | 5 | 3 |
5572 | 70 | F | Neurotypical | − | − | 3 |
5840 | 75.3 | M | Neurotypical | 3 | 5 | − |
5219 | 77 | F | Neurotypical | 4 | − | − |
5171 | 79.2 | M | Neurotypical | 13 | − | − |
5511 | 80.2 | F | Neurotypical | 3 | − | − |
5657 | 82.2 | M | Neurotypical | 10 | 5 | 3 |
5823 | 82.7 | F | Neurotypical | 3 | 5 | 3 |
4976 | 104 | F | Neurotypical | 5 | 5 | 3 |
51 | 30 | 21 | ||||
Alzheimer’s disease | ||||||
1353 | 57 | F | AD (Braak VI) | 7 | 5 | 4 |
1647 | 59 | F | AD (Braak VI) | 7 | 5 | 6 |
2208 | 69 | F | AD (Braak VI) | 5 | 5 | 4 |
4556 | 70 | F | AD (Braak VI) | 5 | 5 | − |
5222 | 80 | F | AD (Braak VI) | 6 | 5 | − |
1456 | 81 | M | AD (Braak VI) | 5 | 5 | 4 |
2207 | 83 | M | AD (Braak VI) | − | − | 3 |
1995 | 89 | F | AD (Braak V) | 8 | 4 | 4 |
1828 | 91 | F | AD (Braak VI) | 5 | 9 | 4 |
48 | 43 | 29 | ||||
Total | 29 individuals | 172 PFC-MDA neurons | 78 HC-MDA neurons | 69 PFC-PTA neurons | ||
Total: 319 neurons |