Table 5.
Correlation between HER2-positive tumours and magnetic resonance imaging features
| HER2 + | χ2 analysis p-value | Univariate analysis | |||
|---|---|---|---|---|---|
| OR (CI 95%)a | p-value | ||||
| No. of patients | 5 | ||||
| Tumour size |
Median (mm) Range (mm) |
25 12–36 |
|||
| ≥ 2 cm | 3/5 | 0.885 | 1.184 (0.192–7.316) | 0.856 | |
| T2 intensity |
Hypointensity Isointensity Hyperintensity |
3/5 2/5 0/5 |
0.322 |
1.844 (0.299–11.39) 2.081 (0.333–12.99) Out of scale |
0.510 0.433 |
| Mass enhancement | 5/5 | 0.268 | Out of scale | ||
| Rim enhancement | 0/5 | 0.087 | Out of scale | ||
| Intralesional necrosis | 1/5 | 0.285 | 0.317 (0.034–2.908) | 0.309 | |
| Perilesional oedema | 0/5 | 0.017 | Out of scale | ||
| Abnormal lymph nodes | 2/5 | 0.910 | 1.111 (0.180–6.875) | 0.910 | |
| Intensity-to-time curve |
Type I Type II Type III |
0/5 1/5 4/5 |
0.720 |
Out of scale 0.721 (0.078–6.674) 2.112 (0.230–19.442) |
0.774 0.509 |
| ADC value |
Very low Low Intermediate |
4/5 1/5 0/5 |
0.681 |
2.575 (0.279–23.75) 0.417 (0.045–3.845) Out of scale |
0.404 0.440 |
| Extent of disease |
Unifocal Multifocal Multicentric |
2/5 2/5 1/5 |
0.857 |
0.796 (0.129–4.915) 1.658 (0.267–10.31) 0.721 (0.078–6.674) |
0.806 0.588 0.774 |
aOR Odds ratio, CI Confidence interval, ADC Apparent diffusion coefficient