FIGURE 3.

Estrogen induced the expression of ZEBRA and BZLF1 mRNA in EBV‐positive nasopharyngeal carcinoma cells. (A) Western blotting showing the ZEBRA protein levels following treatment with E2 in HK1‐EBV‐eGFP, (B) C666‐1, and (C) NPC‐TW01‐EBV‐eGFP. The quantity of the BZLF1 mRNA of (D) HK1‐EBV‐eGFP and (E) C666‐1 cells, which are untreated or treated with E2 (10 nM), are assessed using qRT‐PCR. The BZLF1 mRNA is normalized with that of GAPDH mRNA. The data are expressed as the mean ± standard error (SE). *p < 0.05; **p < 0.01