FIGURE 6.
LINC01605 promotes triple‐negative breast cancer proliferation and metastasis in vivo. (A) Nude mice were implanted with 5 × 105 control (CTL) or LINC01605 ‐KD MDA‐MB‐231 cells. Tumor volumes were measured every 4 days. (B) At day 30, before tumors were excised, tumor weight was measured. (C) LINC01605 levels were measured by quantitative RT‐PCR in breast cancer cells. GAPDH was used as control. (D) Quantifications of lactate dehydrogenase A (LDHA) and Ki‐67 count of tumor by immunohistochemistry. (E) Examples (H&E) of lung metastases from mice. (F) Tumor volume, (G) tumor weight in the experimental groups. (H) Expression of LINC01605, (I) the expressions of LDHA and Ki‐67, and (J) the metastase in the LINC01605‐OE cells‐formed tumors. Scale bar, 100 μm. **p < 0.01. Vec, vector