Table 3.
Prevalence of IgA, IgG, and IgM antibodies to enteroviruses (EV) in the study population by the different age groups.
| Age groups | Control | T1D | p value | All | |||
|---|---|---|---|---|---|---|---|
| n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | ||
| IgA EV antibodies | |||||||
| 0–18.9 y | 5/36 | 13.9 (5.2–30.3) | 16/36 | 44.4 (28.3–61.7) | 0.0098 | 21/72 | 29.2 (19.3–41.2) |
| 19–35.9 y | 2/26 | 7.7 (1.3–26.6) | 13/26 | 50.0 (32.1–67.9) | 0.0055 | 15/52 | 28.8 (17.5–43.3) |
| IgG EV antibodies | |||||||
| 0–18.9 y | 18/36 | 50.0 (34.5–65.5) | 15/36 | 41.7 (26.0–59.1) | NS | 33/72 | 45.8 (34.1–57.9) |
| 19–35.9 y | 11/26 | 42.3 (24.0–62.8) | 15/26 | 57.7 (37.2–76.0) | NS | 26/52 | 50.0 (36.9–63.1) |
| IgM EV antibodies | |||||||
| 0–18.9 y | 1/36 | 2.8 (0.1–16.2) | 2/36 | 5.6 (9.7–20.0) | NS | 3/72 | 4.2 (1.1–12.5) |
| 19–35.9 y | 0/26 | 1/26 | 3.8 (0.2–21.6) | NS | 1/52 | 1.9 (0.1–11.6) | |
Data are presented as the number of EV antibody-positive persons and percentage with the 95% confidence interval (CI) in a row. Cochran-Mantel-Haenszel test, matched for gender, age, and HLA-DR/DQ genotype risk groups for type 1 diabetes (T1D). p values ≤ 0.05 are in bold. NS: not significant.