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. 2022 Jul 31;55:102419. doi: 10.1016/j.redox.2022.102419

Fig. 1.

Fig. 1

Loss of NOX2 does not affect the cellular composition of islets. (A) Representative immunofluorescence stainings of insulin/glucagon, insulin/somatostatin and insulin/CD31 in WT and Nox2−/− islets within the pancreas. Cell nuclei were stained with Hoechst 33,342 (blue). Scale bar: 50 μm. (B-E) Quantitative analysis of insulin- (B), glucagon- (C), somatostatin- (D) and CD31-positive cells (E) in WT and Nox2−/− islets within the pancreas in % of all islet cells (n = 15 each). Mean ± SEM. (F) Representative immunofluorescence stainings of insulin/glucagon, insulin/somatostatin and insulin/CD31 in isolated WT and Nox2−/− islets. Cell nuclei were stained with Hoechst 33,342 (blue). Scale bar: 50 μm. (G-J) Quantitative analysis of insulin- (G), glucagon- (H), somatostatin- (I) and CD31-positive cells (J) in isolated WT and Nox2−/− islets in % of all islet cells (n = 20 each). Mean ± SEM. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)