Fig. 5.

Immunohistochemical stainings of grafted WT and Nox2^−/−islets (A) Representative immunofluorescence stainings of insulin, glucagon, somatostatin and CD31 in WT and Nox2^−/− islets on day 14 after transplantation. Cell nuclei were stained with Hoechst 33,342 (blue). Scale bar: 100 μm. (B-E) Quantitative analysis of insulin- (B), glucagon- (C), somatostatin- (D) and CD31-positive cells (E) in WT and Nox2^−/− islets in % of all islet cells (n = 10 each). Mean ± SEM. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)