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. 2022 Jul 25;12:882300. doi: 10.3389/fonc.2022.882300

Table 4.

Univariable logistic regression analyses of associations between factors and surgical difficulty level.

Low level (n = 86) High level (n = 36) OR (95% CI) P-value
Age (years) 59.3 ± 10.7 56.6 ± 11.1 0.977 (0.943, 1.013) 0.215
Sex 0.001
M 50 33 1 (reference)
F 36 3 0.126 (0.036, 0.444)
BMI (kg/m2) 23.4 ± 2.7 25.5 ± 3.0 1.331 (1.130, 1.569) 0.001
CEA level 0.995
≤5 ng/ml 55 23 1 (reference)
>5 ng/ml 31 13 1.003 (0.446, 2.254)
CA19-9 level 0.935
≤37 U/ml 76 32 1 (reference)
>37 U/ml 10 4 0.950 (0.277, 3.253)
Operation history 0.040
No 58 31 1 (reference)
Yes 28 5 0.334 (0.117, 0.952)
Neoadjuvant chemoradiotherapy 0.260
No 76 29 1 (reference)
Yes 10 7 1.834 (0.638, 5.276)
Tumor location 0.837
Middle 66 27 1 (reference)
Low 20 9 1.100 (0.445, 2.720)
Pathological T stage 0.294
≤T2 35 11 1 (reference)
≥T3 51 25 1.560 (0.680, 3.575)
Pathological N stage 0.178
Negative 45 14 1 (reference)
Positive 41 22 1.725 (0.781, 3.810)
Differentiation 0.257
Well–moderate 72 33 1 (reference)
Poor 14 3 0.468 (0.126, 1.738)
Perineural invasion 0.870
Negative 61 25 1 (reference)
Positive 25 11 1.074 (0.460, 2.507)
Tumor budding
Bd 1 72 28 1 (reference)
Bd 2 8 6 1.929 (0.614, 6.060) 0.261
Bd 3 6 2 0.857 (0.163, 4.503) 0.855
Lymphovascular invasion 0.059
Negative 69 23 1 (reference)
Positive 17 13 2.294 (0.968, 5.436)
Tumor deposit 0.641
Negative 61 24 1 (reference)
Positive 25 12 1.220 (0.529, 2.811)
Tumor size (mm) 25.0 ± 4.1 25.5 ± 3.0 1.029 (0.930, 1.137) 0.582
Pelvic inlet 80.6 ± 8.7 86.5 ± 11.2 1.066 (1.020, 1.114) 0.004
Pelvic depth 123.7 ± 13.8 131.0 ± 13.8 1.039 (1.006, 1.071) 0.011
Pelvic outlet 118.9 ± 12.0 116.2 ± 10.3 0.980 (0.947, 1.014) 0.238
Transverse diameter 129.5 ± 7.8 126.1 ± 8.3 0.947 (0.900, 0.996) 0.034
Interspinous distance 100.5 ± 10.1 95.0 ± 8.3 0.938 (0.896, 0.982) 0.006
Intertuberous distance 117.3 ± 12.8 108.3 ± 11.1 0.941 (0.908, 0.975) 0.001

OR, odds ratio.

The bold values P-value <0.05.