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. 2022 Jul 25;13:886957. doi: 10.3389/fendo.2022.886957

Table 4.

Regression estimates for each of the three PC derived from PCA, representing adiposity (PC1) insulin resistance (PC3) and hypertension (PC2).

Dependent variable β 95%CI p value
PC1 (adiposity) -0.03 (-0.04) - (-0.02) <0.001
PC3 (insulin resistance) -0.01 (-0.02) - (0.001) 0.016
PC2 (hypertension) -0.006 (-0.01) - (0.01) 0.904

PC1 and PC3 showed a strong significant inverse association with mtDNA CN. Regression coefficient β is reported for an increase in 10 mtDNA copies.