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. 2022 Jul 25;13:925757. doi: 10.3389/fpsyt.2022.925757

TABLE 3.

Correlation of PANSS and measured cytokines in each treated group.

TNF-α
IL-33
TGF-β
Risperidone Clozapine Aripiprazole Risperidone Clozapine Aripiprazole Risperidone Clozapine Aripiprazole
PANSS Total Rho = −0.063 P = 0.793 Rho = −0.090 P = 0.707 Rho = 0.603 P = 0.005** Rho = 0.459 P = 0.042* R = 0.148 P = 0.533 R = −0.292 P = 0.212 Rho = −0.187 P = 0.430 R = 0.243 P = 0.301 R = −0.255 P = 0.277
PANSS Positive Rho = 0.145 P = 0.543 Rho = 0.051 P = 0.830 Rho = 0.593 P = 0.006** Rho = 0.374 P = 0.104 Rho = 0.160 P = 0.500 Rho = −0.306 P = 0.189 Rho = −0.107 P = 0.655 Rho = 0.302 P = 0.196 Rho = −0.223 P = 0.344
PANSS Negative Rho = −0.055 P = 0.818 Rho = 0.023 P = 0.923 Rho = 0.555 P = 0.011* Rho = 0.431 P = 0.058* Rho = 0.258 P = 0.271 R = −0.283 P = 0.227 Rho = −0.231 P = 0.327 Rho = 0.486 P = 0.030* R = −0.188 P = 0.428
PANSS General Rho = −0.083 P = 0.729 Rho = 0.019 P = 0.937 Rho = 0.608 P = 0.004** Rho = 0.344 P = 0.138 R = 0.171 P = 0.471 R = −0.208 P = 0.379 R = −0.233 P = 0.257 R = 0.185 P = 0.435 R = −0.215 P = 0.362

The Shapiro-Wilk normality test. Pearson’s correlation or the Spearman’s correlation coefficient. Pearson’s correlation coefficient is denoted by “R” and Spearman’s correlation coefficient is denoted by “Rho”. If R or Rho is >0.5, it means that there is a positive and strong correlation, and the condition for it to be statistically significant is that p is <0.05.

PANSS, Positive and Negative Syndrome Scale; IL, Interleukin; TNF, Tumor Necrosis Factor; TGF, Transforming growth factor.