TABLE 5.
Correlation of observed metabolic variables and measured cytokines in each group of patients.
| TNF-α |
IL-33 |
TGF-β |
|||||||
| Risperidone | Clozapine | Aripiprazole | Risperidone | Clozapine | Aripiprazole | Risperidone | Clozapine | Aripiprazole | |
| Prolactin (mIU/L) | Rho = 0.178 P = 0.452 |
Rho = −0.061 P = 0.799 |
Rho = −0.093 P = 0.698 |
Rho = −0.190 P = 0.423 |
Rho = 0.100 P = 0.675 |
Rho = 0.149 P = 0.531 |
Rho = 0.006 P = 0.979 |
Rho = 0.373 P = 0.105 |
Rho = 0.211 P = 0.371 |
| Cholesterol (mmol/l) | Rho = −0.002 P = 0.995 |
Rho = −0.096 P = 0.686 |
Rho = −0.063 P = 0.791 |
Rho = 0.034 P = 0.920 |
R = −0.019 P = 0.935 |
R = −0.239 P = 0.311 |
Rho = 0.050 P = 0.835 |
R = 0.316 P = 0.175 |
R = −0.351 P = 0.129 |
| Triglycerides (mmol/l) | Rho = 0.208 P = 0.378 |
Rho = 0.169 P = 0.477 |
Rho = 0.173 P = 0.466 |
Rho = 0.240 P = 0.308 |
R = −0.061 P = 0.799 |
Rho = 0.033 P = 0.890 |
Rho = 0.389 P = 0.090 |
R = 0.376 P = 0.102 |
Rho = −0.075 P = 0.753 |
| HDL(mmol/l) | Rho = −0.212 P = 0.369 |
Rho = −0.208 P = 0.379 |
Rho = −0.114 P = 0.634 |
Rho = −0.190 P = 0.421 |
Rho = −0.050 P = 0.833 |
R = 0.190 P = 0.424 |
Rhov−0.427 Pv0.061 |
Rho = −0.029 P = 0.905 |
R = 0.323 P = 0.165 |
| LDL(mmol/l) | Rho = −0.063 P = 0.791 |
Rho = −0.086 P = 0.719 |
Rho = −0.128 P = 0.591 |
Rho = 0.025 P = 0.917 |
R = −0.170 P = 0.474 |
R = −0.383 P = 0.096 |
R = 0.057 P = 0.810 |
R = 0.227 P = 0.336 |
R = −0.525 P = 0.018* |
| Glucose(mmol/l) |
Rho = 0.515 P = 0.020* |
Rho = 0.161 P = 0.497 |
Rho = 0.026 P = 0.914 |
Rho = 0.700 P = 0.001*** |
Rho = 0.439 P = 0.053 |
Rho = −0.084 P = 0.724 |
Rho = 0.431 P = 0.028* |
Rho = 0.227 P = 0.336 |
Rho = −0.333 P = 0.152 |
| Insulin(mIU/L) | Rho = 0.223 P = 0.345 |
Rho = 0.128 P = 0.591 |
Rho = 0.336 P = 0.150 |
Rho = −0.038 P = 0.875 |
R = 0.001 P = 0.998 |
Rho = −0.075 P = 0.753 |
Rho = 0.154 P = 0.516 |
R = 0.615 P = 0.004** |
Rho = −0.095 P = 0.691 |
| BMI(kg/m2) | Rho = 0.069 P = 0.772 |
Rho = 0.685 P = 0.001*** |
Rho = −0.150 P = 0.527 |
Rho = −0.001 P = 0.997 |
R = 0.623 P = 0.003** |
R = −0.129 P = 0.588 |
R = 0.031 P = 0.897 |
R = 0.307 P = 0.188 |
R = −0.302 P = 0.196 |
| HOMA(mmol/l* mIU/L/22.5) |
Rho = 0.499 P = 0.025* |
Rho = 0.229 P = 0.330 |
Rho = 0.302 P = 0.196 |
Rho = 0.120 P = 0.615 |
Rho = 0.012 P = 0.960 |
Rho = −0.108 P = 0.649 |
Rho = 0.310 P = 0.184 |
Rho = 0.654 P = 0.002** |
Rho = −0.157 P = 0.508 |
| WHR (cm) | Rho = −0.171 P = 0.470 |
Rho = 0.120 P = 0.615 |
Rho = −0.140 P = 0.556 |
Rho = 0.333 P = 0.152 |
Rho = 0.172 P = 0.581 |
Rho = −0.247 P = 0.294 |
Rho = −0.347 P = 0.134 |
Rho = 0.105 P = 0.565 |
Rho = −0.151 P = 0.526 |
The Shapiro-Wilk normality test. Pearson’s correlation coefficient or Spearman’s correlation coefficient. Pearson’s correlation coefficient is denoted by “R” and Spearman’s correlation coefficient is denoted by “Rho”. If R or Rho is > 0.5, it means that there is a positive and strong correlation, and the condition for it to be statistically significant is that p is <0.05.
HDL, High density lipoprotein; LDL, Low density lipoprotein; BMI, Body Mass Index; HOMA index, Homeostatic Model Assessment for Insulin Resistance; WHR, Waist-to-hip ratio; IL, Interleukin; TNF, Tumor Necrosis Factor; TGF, Transforming growth factor.