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. 2022 Jul 25;12:885236. doi: 10.3389/fonc.2022.885236

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Copyright © 2022 Wongpattaraworakul, Gibson-Corley, Choi, Buchakjian, Lanzel, Rajan KD and Simons

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prognostic impact of combined EGFR and CD8 expression in OSCCs. (A) Shown are images of no [0], low [1+], moderate [2+], and strong [3+] CD8 expression scores. (B) Kaplan-Meier estimates of the overall survival of CD8+ (2+, 3+, 1+) and CD8- (0) patients. (C) Percentages of tumors with CD8+ and CD8- expression based on EGFR status. (D, E) Kaplan-Meier estimates of overall survival of CD8+ and CD8- patients based on EGFR+ (D) or EGFR- (E) tumor expression. (F) Percentages of tumors with CD8+ and CD8- expression based on EGFR and CD3 status. HR, hazard ratio; CI, 95% confidence interval.