Table 1.
Clinicopathological features of patients based on EGFR status.
| Characteristics | Total Patients (n) | EGFR Status (n=143) | p-value | |
|---|---|---|---|---|
| EGFR+ | EGFR- | |||
| Number of evaluations | 146 | 59 | 84 | |
| Sex | ||||
| Male | 85 (58.22%) | 34 (57.63%) | 48 (57.14%) | 0.91 |
| Female | 61 (41.78%) | 25 (42.37%) | 36 (42.86%) | |
| Average age [ ± stdev]* | ||||
| Male | 58.16 [11.05] | 58.03 [13.03] | 58.33 [9.94] | 0.95 |
| Female | 66.41 [17.36] | 67.04 [16.31] | 65.97 [18.29] | |
| Smoking History | ||||
| Active smoker | 64 (44.14%) | 24 (40.68%) | 37 (44.58%) | 0.32 |
| Never smoker | 50 (34.48%) | 22 (37.29%) | 28 (33.73%) | |
| Quit < 10 Years | 13 (8.97%) | 3 (5.08%) | 10 (12.05%) | |
| Quit > 10 Years | 18 (12.41%) | 10 (16.95%) | 8 (9.64%) | |
| N/A | 1 | |||
| Tumor Site | ||||
| Alveolar | 24 (16.44%) | 9 (15.25%) | 14 (16.67%) | 0.41 |
| Floor of mouth | 32 (21.92%) | 11 (18.64%) | 21 (25%) | |
| Tongue | 55 (37.67%) | 27 (45.76%) | 27 (32.14%) | |
| Other | 35 (23.97%) | 12 (20.34%) | 22 (26.19%) | |
| T Stage | ||||
| T1 | 43 (29.45%) | 22 (37.29%) | 21 (25%) | 0.27 |
| T2 | 43 (29.45%) | 16 (27.12%) | 25 (29.76%) | |
| T3/T4 | 60 (41.10) | 21 (35.59%) | 38 (45.24) | |
| N Stage | ||||
| N0 | 74 (50.68%) | 27 (45.76%) | 46 (54.76%) | 0.16 |
| N1/2a | 29 (19.86%) | 16 (27.12%) | 12 (14.29%) | |
| N2b/2c/3 | 43 (29.45%) | 16 (27.12%) | 26 (30.95%) | |
| Differentiation | ||||
| Well | 15 (10.49%) | 3 (5.26%) | 12 (14.46%) | 0.22 |
| Moderate | 92 (64.34%) | 38 (66.67%) | 51 (61.45%) | |
| Poor | 36 (25.17%) | 16 (28.07%) | 20 (24.1%) | |
| N/A | 3 | |||
| Perineural invasion | ||||
| Yes | 73 (50.34%) | 35 (59.32%) | 38 (45.24%) | 0.1 |
| No | 72 (49.66%) | 24 (40.68%) | 46 (54.76%) | |
| N/A | 1 | |||
| Lymphovascular invasion | ||||
| Yes | 54 (37.24%) | 25 (42.37%) | 29 (34.52%) | 0.34 |
| No | 91 (62.76%) | 34 (57.63%) | 55 (65.48%) | |
| N/A | 1 | |||
| Bone invasion | ||||
| Yes | 44 (30.34%) | 15 (25.42%) | 29 (34.52%) | 0.25 |
| No | 101 (69.66%) | 44 (74.58%) | 55 (65.48%) | |
| N/A | 1 | |||
| Local recurrence | ||||
| Yes | 45 (30.82%) | 20 (33.90%) | 25 (29.76%) | 0.6 |
| No | 101 (69.18%) | 39 (66.10%) | 59 (70.24%) | |
*Average age at diagnosis