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. 2022 Jul 25;13:918605. doi: 10.3389/fendo.2022.918605

Figure 6.

Figure 6

Construction of PPI network and identification of hub genes. (A) The PPI network of 13 differentially expressed PRGs was constructed by using String database. It contains 13 nodes and 35 edges. The average node degree is 5.38, and the PPI enrichment P-value is less than 1.0e-16. (B) First eight hub genes of the PPI network. First eight genes with the highest degree identified by Cytoscape software and CytoHubba. These genes are ranked in descending order from red to yellow. PPI, protein–protein interaction; PRGs, pyroptosis-related genes.