Table 2.
The 13 differentially expressed pyroptosis-related genes in diabetic retinopathy samples compared to normal samples.
| Gene symbol | logFC | Changes | P-value | Adjusted P-value | Gene id |
|---|---|---|---|---|---|
| CTSG | -2.04863800 | Down | 3.474745e-12 | 3.535901e-09 | 1511 |
| CASP4 | 1.18248927 | Up | 3.190990e-09 | 5.237341e-07 | 837 |
| TNFRSF21 | 0.97602261 | Up | 1.671004e-07 | 8.553391e-06 | 27242 |
| PYCARD | 0.77897161 | Up | 8.722862e-07 | 2.709519e-05 | 29108 |
| CASP1 | 1.23521922 | Up | 8.987948e-07 | 2.748238e-05 | 834 |
| CASP3 | 1.08640598 | Up | 1.156639e-06 | 3.351356e-05 | 836 |
| GBP1 | 1.64253837 | Up | 3.128202e-06 | 6.727089e-05 | 2633 |
| TLR4 | 0.71026963 | Up | 3.722308e-05 | 4.113837e-04 | 7099 |
| CARD8 | 0.91154823 | Up | 7.318641e-05 | 6.827511e-04 | 22900 |
| NLRP3 | 0.72061228 | Up | 6.323034e-04 | 3.673396e-03 | 114548 |
| GBP2 | 0.67696609 | Up | 6.970046e-04 | 3.974848e-03 | 2634 |
| GBP5 | 0.96463926 | Up | 2.668633e-03 | 1.181312e-02 | 115362 |
| GZMA | 1.16170618 | Up | 5.368367e-03 | 2.079660e-02 | 3001 |
PRGs, pyroptosis-related genes; DR, diabetic retinopathy; FC, fold change.