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. 2022 Jul 25;13:918605. doi: 10.3389/fendo.2022.918605

Table 4.

PPI network of the top 8 hub genes.

Rank Gene symbol Score Gene id Gene name
1 CASP1 196 834 caspase-1
2 NLRP3 192 114548 NLR family pyrin domain containing 3 caspase-4
3 CASP4 168 837 PYD and CARD domain containing toll like receptor 4
4 PYCARD 144 29108 NLR family pyrin domain containing 3 caspase-4
5 TLR4 122 7099 PYD and CARD domain containing toll like receptor 4
6 CASP3 121 836 caspase-3
7 GBP2 48 2634 guanylate binding protein 2
8 GBP1 48 2633 guanylate binding protein 1

PPI, protein-protein interaction.