Fig. 1.

Arginine metabolic alternations of BMECs in response to IFN-γ by targeted metabolomics. BMECs were treatment with 10 ng/mL IFN-γ for 24 h. Targeted metabolomics was used to detect the changes of metabolites related to intracellular arginine metabolic pathway upon IFN-γ treatment. Bars represent mean values with error bars to represent SD from twelve independent replicates. Differences between mean values were assessed by two-tailed Student’s t-test. *p < 0.05; **p < 0.01; ***p < 0.001, compared to control