Figure 1.

Comparison of the structures of PD-1 in complex with nivolumab-Fab (A) (PDB code: 5WT9), pembrolizumab-Fab (B) (PDB code: 5JXE), and tislelizumab-Fab (C,D) (PDB code: 7BXA, 7CGW). Images were acquired from the Protein Data Bank and relevant research was conducted by Tan S et al, Na Z et al, Lee SH et al, and Hong Y et al, respectively.^13-18 L chain, light chain; H chain, heavy chain; LCDRs, complementary determining regions of the light chain; HCDRs, complementary determining regions of the heavy chain; PD-1, programmed death protein 1.