Table 1.
Laboratory Data at the Time of Diagnosis.
| Laboratory test
(Reference value) |
Diagnosis of
RS3PE syndrome |
Diagnosis of HCC |
|---|---|---|
| Leukocytes (3900-9800/μL) | 3900/μL | 5500/μL |
| Hemoglobin (13.4-17.6 g/dL) | 13.6 g/dL | 13.8 g/dL |
| Platelets (15-40 *104/μL) | 17.4*104/μL | 17.1*104/μL |
| Albumin (4.1-5.1 g/dL) | 2.5 g/dL | 3.7 g/dL |
| Total bilirubin (0.2-1.2 mg/dL) | 0.5 mg/dL | 0.6 mg/dL |
| AST (13-30 U/L) | 33 U/L | 22 U/L |
| ALT (10-42 U/L) | 32 U/L | 16 U/L |
| CRP (0.00-0.30 mg/dL) | 9.67 mg/dL | 0.24 mg/dL |
| ESR (0-10 mm/h) | 36 mm/h | Not measured |
| Ferritin (18-250 ng/mL) | 503.3 ng/mL | Not measured |
| PT activation (80%-100%) | 85.9% | 87.6% |
| AFP (<10 ng/mL) | Not measured | 1.7 ng/mL |
| PIVKA-II (<40 mAU/mL) | Not measured | 23 mAU/mL |
| IgG (815-1800 mg/dL) | 1449 mg/dL | 1553 mg/dL |
| IgM (32-190 mg/dL) | 54 mg/dL | 88 mg/dL |
| RF (0-15 IU/mL) | <5 IU/mL | Not measured |
| ANA (negative) | 320 | Not measured |
| Anti-CCP (0.0-4.4 U/mL) | 1.0 U/mL | Not measured |
| PR3-ANCA (0.0-3.4 EU) | <1.0 EU | Not measured |
| MPO-ANCA (0.0-3.4 EU) | <1.0 EU | Not measured |
| Hyaluronic acid (≤50.0 ng/mL) | Not measured | 56.0 ng/mL |
| M2BPGi (<1.00) | Not measured | 1.27 |
| 7S domain of type IV collagen (≤4.4 ng/mL) | Not measured | 5.4 ng/mL |
| Fib-4 index (<1.3 points) | 2.41 points | 2.48 points |
AST, aspartate transaminase; ALT, alanine aminotransferase; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; PT, prothrombin; AFP, alpha-fetoprotein; PIVKA-II, protein induced by vitamin K absence or antagonist-II; RF, rheumatoid factor; IgG, immunoglobulin G; IgM, immunoglobulin M; ANA, antinuclear antibody; Anti-CCP, anti-cyclic citrullinated peptide; PR3-ANCA, proteinase-3 antineutrophil cytoplasmic antibody; MPO-ANCA, myeloperoxidase antineutrophil cytoplasmic antibody; M2BPGi, Mac-2 binding protein glycan isomer; Fib-4 index, Fibrosis-4 index