Figure 2.

Female patient, 65 years old at time of imaging studies; progression from SMM to MM. First appearance of two focal lesions on MRI (see arrows): a) in the third lumbar vertebral body (L3) measuring 7 × 8 mm and b) in the right femoral neck measuring 3.3 × 2.5 cm; this finding in combination with bone destruction (cortical breach is already visible on MRI).

DWI, diffusion-weighted imaging; MM, multiple myeloma; MRI, magnetic resonance imaging; SMM, smoldering multiple myeloma; T1w, T1-weighted image; T2w FS, T2-weighted image with fat suppression