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Dose–response meta-analysis of changes in glycemic control according to CoQ10 in the treatment and control groups at the end of the trials. (a) fasting glucose, (b) HbA1c, (c) fasting insulin, (d) HOMA-IR. The average curve (solid line) with 95% confidence limits (dotted lines) was estimated with a 1-stage random-effects restricted cubic spline model, using 0 mg/day as referent. Abbreviations: CoQ10, coenzyme Q10.
