Figure 2.

Venn diagram depicting significantly differentially expressed transcripts in the small intestine crypt, small intestine villus, or colon. Mice were treated with 1,25(OH)₂D₃ (10 ng/g, 4 h) and RNA from the three compartments was used for RNA-seq analysis. Differential expression was determined using DeSeq2 (5% FDR). The percentage of upregulated (UP) and downregulated transcripts (DN) are prevented for the total number of differentially expressed transcripts by tissue and for the compartment-specific transcripts. 1,25(OH)2D3, 1,25-dihydroxyvitamin D3.