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. 2022 Jul;10(13):739. doi: 10.21037/atm-21-4779

Figure 7.

Figure 7

Sal B increases mTOR and protein kinase B (AKT) signaling activation by upregulating STC1 expression. Western blot analysis of (A) phosphorylated (p)-mTOR and total (t)-mTOR expression; (B) p-AKT and t-AKT expression in rats; (C) p-mTOR and t-mTOR expression; and (D) p-AKT and t-AKT expression in HUVECs. (n=3). Data are mean ± SD. *, P<0.05, **, P<0.01. mTOR, mammalian target of rapamycin; Sal B, salvianolic acid B; STC1, Sal B increased stanniocalcin 1; HUVEC, human umbilical vein endothelial cell; SH, sham operation rats intraperitoneally injected with saline; OG, rats with middle cerebral artery occlusion intraperitoneally injected with saline; Sal B-L, MCAO rats intraperitoneally injected with a low (L) dose of Sal B; Sal B-H, MCAO rats intraperitoneally injected with a high (H) dose of Sal B.