Table 3. Seven function-related proteins that were validated in the parallel reaction monitoring analysis.
| Peptides | ID | Protein | PRM | DIA | Related diseases | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| ROC | Disease/CON | P value | ROC | Disease/CON | P value | |||||
| AVLDGCSCCLVCAR | P48745 | NOV_HUMAN | 0.83 | 2.84 | 0.02 | 0.78 | 2.14 | 0.02 | GDM | |
| LLADPTGAFGK | P30044 | PRDX5_HUMAN | 0.74 | 0.57 | 0.02 | 0.76 | 0.55 | 0.03 | GDM | |
| SPLNDFQVLR | P26927 | HGFL_HUMAN | 0.72 | 1.77 | 0.02 | 0.71 | 1.47 | 0.04 | GDM | |
| VADPAYLPTQQDVLR | P50148 | GNAQ_HUMAN | 0.78 | 0.44 | 0.01 | 0.83 | 0.55 | 0.01 | SA | |
| LFVSGACDASAK | P62873 | GBB1_HUMAN | 0.80 | 0.55 | 0.00 | 0.74 | 0.65 | 0.03 | SA | |
| TDTGVSLQTYDDLLAK | Q99988 | GDF15_HUMAN | 0.81 | 0.41 | 0.02 | 0.85 | 0.28 | 0.00 | SA | |
| MFDVGGQR | P08754 | GNAI3_HUMAN | 0.75 | 0.63 | 0.03 | 0.81 | 0.61 | 0.01 | SA | |
PRM, parallel reaction monitoring; DIA, data-dependent acquisition; ROC, receiver operating characteristic curve; CON, control; GDM, gestational diabetes mellitus.