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. 2022 Jul;10(13):736. doi: 10.21037/atm-21-3497

Table 3. Seven function-related proteins that were validated in the parallel reaction monitoring analysis.

Peptides ID Protein PRM DIA Related diseases
ROC Disease/CON P value ROC Disease/CON P value
AVLDGCSCCLVCAR P48745 NOV_HUMAN 0.83 2.84 0.02 0.78 2.14 0.02 GDM
LLADPTGAFGK P30044 PRDX5_HUMAN 0.74 0.57 0.02 0.76 0.55 0.03 GDM
SPLNDFQVLR P26927 HGFL_HUMAN 0.72 1.77 0.02 0.71 1.47 0.04 GDM
VADPAYLPTQQDVLR P50148 GNAQ_HUMAN 0.78 0.44 0.01 0.83 0.55 0.01 SA
LFVSGACDASAK P62873 GBB1_HUMAN 0.80 0.55 0.00 0.74 0.65 0.03 SA
TDTGVSLQTYDDLLAK Q99988 GDF15_HUMAN 0.81 0.41 0.02 0.85 0.28 0.00 SA
MFDVGGQR P08754 GNAI3_HUMAN 0.75 0.63 0.03 0.81 0.61 0.01 SA

PRM, parallel reaction monitoring; DIA, data-dependent acquisition; ROC, receiver operating characteristic curve; CON, control; GDM, gestational diabetes mellitus.