Table 3. Prediction of response to medication and DBS based on the neuroimaging pattern.
| Motor symptoms severity | Drug response | DBS response | |||
|---|---|---|---|---|---|
| Classification model | Regression model | Classification model | Regression model | ||
| UPDRS-III total score | 32/78 (41.0%) | R=0.04, P=0.70 | 17/33 (51.5%) | R=−0.14, P=0.21 | |
| Tremor score | 43/78 (55.1%) | R=−0.34, P<0.01* | 20/33 (60.6%) | R=0.18, P=0.35 | |
| Akinetic/rigidity score | 38/78 (48.7%) | R=−0.04, P=0.75 | 23/33 (69.7%) | R=0.20, P=0.25 | |
| PIGD score | 42/78 (53.9%) | R=0.24, P=0.04* | 15/33 (45.5%) | R=−0.18, P=0.30 | |
*: statistical significance. DBS, deep brain stimulation; UPDRS, unified Parkinson’s disease rating scale; PIGD, postural instability and gait disorders.