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. 2022 Jul;10(13):737. doi: 10.21037/atm-22-845

Table 2. Fifteen hub genes.

Gene symbol Description log2FC Adjusted P value Regulation
Hmox1 Heme oxygenase 1 4.761 2.753e-05 Up
Cxcl1 Chemokine (C-X-C motif) ligand 1 5.616 3.556e-04 Up
Cxcl12 Chemokine (C-X-C motif) ligand 12 −3.238 5.987e-08 Down
Igfbp5 Insulin-like growth factor binding protein 5 −3.481 2.121e-03 Down
Itgam Integrin alpha M 4.758 5.308e-05 Up
Klhl21 Kelch-like 21 4.311 1.141e-10 Up
F8 Coagulation factor VIII −3.626 7.876e-07 Down
Lcn2 Lipocalin 2 6.298 1.599e-10 Up
Mapk14 Mitogen-activated protein kinase 14 4.988 1.030e-06 Up
Nedd4l Neural precursor cell expressed, developmentally down-regulated gene 4-like 3.150 5.767e-07 Up
Pnpla2 Patatin-like phospholipase domain containing 2 4.134 4.713e-04 Up
Serpina1a Serine (or cysteine) peptidase inhibitor 7.563 3.742e-25 Up
Serpina3n Serine (or cysteine) peptidase inhibitor, clade A, member 3N 4.963 9.239e-07 Up
Socs3 Suppressor of cytokine signaling 3 4.914 2.297e-09 Up
Spp1 Secreted phosphoprotein 1 3.503 6.272e-07 Up

FC, fold change.