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. 2022 Jul;10(13):745. doi: 10.21037/atm-22-2766

Table 4. Subgroup analysis between the elder and middle-young populations.

Items 1999–2000 2017–2018
≥65 <65 P value ≥65 <65 P value
N (%) 201 (69.6) 88 (30.4) 239 (62.6) 143 (37.4)
SBP (mmHg) 145 [132–161] 134 [122–146] <0.001 137 [127–153] 129 [118–139] <0.001
DBP (mmHg) 69 [61–76] 76 [69–83] 0.001 68 [58–77] 75 [67–81] <0.001
HTN control rate (%) 16.8 29.9 0.034 29.4 42.7 0.018
Pulse (p.m.) 68 [62–76] 70 [62–84] 0.185 66 [60–72] 70 [62–82] <0.001
Proportion of pulse ≤60 p.m. (%) 24.3 23.5 0.895 31.1 18.8 0.012
Total cholesterol (mmol/L) 5.0 [4.4–5.8] 5.5 [4.6–6.1] 0.065 4.2 [3.6–4.9] 4.4 [3.8–5.3] 0.127
Triglycerides (mmol/L) 1.6 [1.2–2.3] 2.1 [1.5–3.2] 0.022 1.2 [0.8–1.6] 1.42 [1.0–1.8] 0.065
LDL-C (mmol/L) 3.0 [2.6–3.5] 2.9 [2.5–3.7] 0.968 2.2 [1.7–2.6] 2.6 [2.0–3.3] 0.009
LDL-C control rate (%) 6.8 3.6 0.558 30.1 19.4 0.117
HDL-C (mmol/L) 1.1 [1.0–1.4] 1.1 [0.9–1.3] 0.311 1.2 [1.0–1.5] 1.1 [1.0–1.4] 0.016
Creatinine (μmol/L) 79.6 [61.9–97.2] 70.7 [53–79.6] 0.001 97.3 [76.9–118.5] 76.9 [66.3–88.8] <0.001
Urea nitrogen (mmol/L) 6.4 [5–8.2] 5.4 [4.6–6.8] 0.001 6.8 [5.4–9.3] 5.4 [4.3–6.4] <0.001
Glucose (mmol/L) 5.4 [5.00–6.2] 5.4 [4.8–6.8] 0.773 5.6 [5.1–6.9] 5.63 [5.1–7.1] 0.921
Glycohemoglobin (%) 5.7 [5.3–6.3] 5.6 [5.3–6.8] 0.758 6.1 [5.7–6.8] 5.9 [5.5–6.8] 0.099
ACEI/ARB (%) 40.8 35.2 0.372 58.6 55.2 0.524
β-blocker (%) 33.8 29.6 0.474 61.1 58 0.557
CCB (%) 29.9 14.8 0.007 28 16.1 0.008
Diuretic (%) 35.8 21.6 0.017 38.5 27.3 0.025
Statin (%) 30.9 34.1 0.586 69.5 55.2 0.005

Data are presented as percent or median [25% percentile, 75% percentile]. SBP, systolic blood pressure; DBP, diastolic blood pressure; HTN, hypertension; p.m., per minute; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker.