Table 3. F₁ generation (Cohort 1A)—male organ weight and relative organ coefficient.

Test Items	ZnO NPs (mg/kg bw/d)
	0	7	50	350
Final body weight (mean ± SD, g)	604±52	594±31	576±40	533±62*
Organ weight (mean ± SD, g)
Liver	16.27±1.85	15.81±1.40	15.53±2.05	14.46±2.04*
Heart	2.01±0.13	1.85±0.14	1.85±0.19	1.73±0.22*
Spleen	1.05±0.18	1.10±0.15	1.05±0.15	0.87±0.18*
Lung	2.32±0.41	2.31±0.25	2.33±0.60	1.92±0.39
Kidney	4.02±0.40	3.77±0.36	3.77±0.47	3.56±0.45*
Brain	2.18±0.12	2.15±0.16	2.14±0.11	2.00±0.18*
Testis	3.69±0.66	3.80±0.37	3.85±0.42	3.28±0.60*
Epididymis	2.14±0.50	1.96±0.57	2.07±0.42	1.95±0.48*
Organ coefficient (mean ± SD, %)
Liver	2.69±0.16	2.66±0.19	2.69±0.25	2.72±0.33
Heart	0.33±0.03	0.31±0.02	0.32±0.03	0.33±0.03
Spleen	0.17±0.03	0.18±0.02	0.18±0.03	0.16±0.03
Lung	0.39±0.07	0.39±0.04	0.41±0.11	0.36±0.07
Kidney	0.67±0.04	0.63±0.05	0.65±0.07	0.67±0.09
Brain	0.36±0.03	0.36±0.03	0.37±0.03	0.38±0.05
Testis	0.61±0.10	0.64±0.06	0.67±0.06	0.62±0.13
Epididymis	0.36±0.09	0.33±0.10	0.36±0.08	0.37±0.10

Statistical significance is represented as *P<0.05 as compared with control group. ZnO NPs, zinc oxide nanoparticles.