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Panels illustrate differences between participants with posttraumatic stress disorder (PTSD, blue), major depressive disorder (MDD, purple), and healthy adults (HA, gray) in in vivo mGluR5 availability. Data are displayed for four brain regions (Study ROIs used in primary analyses): orbitofrontal cortex (OFC; top left), ventromedial prefrontal cortex (vmPFC; bottom left), dorsolateral prefrontal cortex (dlPFC; top right), hippocampus (bottom right).
