Table 6.
Effect of Curative Doses of Senna alata Extracts on Oxidative Stress Markers in Plasmodium Berghei Infected Mice.
| Treatments | SOD (UI/L) | CAT (IU/L) | GPx (U/mg protein) | GSH (mg/dL) | Lipid peroxides (mg/dL) |
|---|---|---|---|---|---|
| Normal control | 9.14 ± 0.12 | 0.69 ± 0.09 | 2.56 ± 0.21 | 4.46 ± 0.77 | 5.62 ± 1.01 |
| Negative control | 7.11 ± 0.45 | 0.34 ± 0.06 | 1.87 ± 0.39 | 1.22 ± 0.18 | 17.25 ± 3.53 |
| 25 mg/kg/day Chloroquine phosphate (CQ) | 8.42 ± 1.09 | 0.42 ± 0.12 | 2.39 ± 0.15a* | 3.81 ± 0.50a | 6.58 ± 0.65a |
| 200 mg/kg/day SAE | 10.62 ± 1.13ab* | 0.55 ± 0.15a** | 3.33 ± 0.16ab | 4.60 ± 0.67ab** | 6.86 ± 1.26a |
Values are presented as mean ± SD of six(6) determinations.
a < 0.001, a* < 0.01 compared with negative control.
b < 0.001, b* < 0.01, b** < 0.05 compared to CQ group.