Table 2.
Results of prolonged weaning – comparison of patients with unsuccessful and successful decannulation.
| Results of prolonged weaning | All patients (n = 532) | Decannulation failure (n = 216) | Decannulation success (n = 316) | p value a |
|---|---|---|---|---|
| Weaning completion to decannulation (days) | 5 (3–11) | – | 5 (3–11) | – |
| Decannulation to discharge (days) | 13 (8–21) | – | 13 (8–21) | – |
| Secondary decannulation failures | 30 (5.6) | 30 (13.9) | – | – |
| Decannulation to re-cannulation (days) | 2 (1–4) | 2 (1–4) | – | – |
| Weaning success | 311 (58.5) | 91 (42.1) | 220 (69.6) | < 0.01 b |
| Weaning failure | 221 (41.5) | 125 (57.9) | 96 (30.4) | < 0.01 b |
| Home mechanical ventilation – NIV | 96 (18.0) | – | 96 (30.4) | – |
| Home mechanical ventilation – IMV | 125 (23.5) | 125 (57.9) | – | – |
| Duration of mechanical ventilation (days)* | 44 (32–57) | 47 (33–66) | 41 (31–54) | <0.01 c |
| PEG feeding tube placement | 280 (52.6) | 165 (76.4) | 115 (36.4) | <0.01 b |
| NPO recommendation on discharge | 198 (37.2) | 152 (70.4) | 46 (14.6) | <0.01 b |
IMV, invasive mechanical ventilation; NIV, non-invasive mechanical ventilation; NPO, nil per os; PEG, percutaneous endoscopic gastrostomy.
Continuous variables are presented as median (– interquartile range [IQR]); categorical variables are presented as numbers (%).
a
p value for differences between patients with unsuccessful and successful decannulation. Significant values are in bold.
b
Chi-square test.
c
Mann–Whitney U-test.
*
Time spent on invasive ventilation, defined as the period between intubation and prolonged ventilator weaning completion.